What Exactly Is This “Great Reset” People Keep Talking About?

Buckle your seat belts for this one because it’s more chilling than any horror movie you’ve ever seen. You’ve heard your “crazy” friend at work bring it up in conversation. Perhaps you heard it briefly mentioned on TV the other day. And now you’re left wondering, “Just what on earth is The Great Reset?”

Meet The World Economic Forum (WEF)

You’ve heard of the WEF before. They’ve been in the news quite a bit for the past year or so. The reason? The Great Reset initiative. It is there that a man by the name of Klaus Schwabb runs the show. Schwabb founded the WEF and is one of the most powerful men in the world.

Each year the World Economic Forum hosts an event at a ski resort in the mountains of Switzerland where “the self-proclaimed global elite” meet to discuss global problems they can all work together to “fix.”

Generally, WEF invites 1500 people from roughly 70 countries to attend. All the attendees play major roles in various sectors of society, with a large portion of those invited being major players in the worlds of politics and business. 

In 2020, Schwabb released a book titled COVID-19: The Great Reset, in which he lays out his plans for what he believes needs to happen next.  

Now, Let’s Talk About Agendas

First, you need to understand one thing: the World Economic Forum and the United Nations march together hand in hand. In short, they’re two sides of the same coin.

The United Nations previously announced two separate agendas eerily similar to The Great Reset that contain many of the same components. These two UN agendas, Agenda 21 and Agenda 2030, include plans for what needs to happen on earth by 2021 and 2030 (there’s also an Agenda 2050, by the way).

Agenda 2030 has publicly stated goals of promoting racial and gender equality, eradicating global poverty, and abolishing violence, hate, and war from the globe. It also states it will reduce natural resource use in every country and reduce greenhouse gas emissions in every industrialized country. 

And How Do You Suppose Agenda 2030 Would Accomplish Those Goals?

Suppose you’re a lumberjack. A global organization has just stated you’re no longer permitted to cut down trees to “reduce natural resource use.” You’re now out of a job and can’t afford to feed your newborn daughter.

Or, let’s say you’re a farmer. A global organization has just stated that your cows produce too much methane. They’re all slaughtered and left to rot in a field (we’ll get to why later). You’ve now lost a significant investment, your primary source of income, and are out of a job. Farmers in non-industrialized nations are permitted to raise cattle. But you’re an American, so you are not.

Why? Because we need to “reduce greenhouse gas emissions in every industrialized country.”

Here’s another example. You’re an American with unalienable rights, a Constitution, and the Bill of Rights. You have the Declaration of Independence and a long history of fierce protection of freedom. Protection of freedom necessitates the possession of arms.

But now, a global organization has landed troops on your shores. Why? To “abolish violence.” The organization deems your possession of arms as a hindrance to such. Therefore, the organization will take measures against you to abolish violence.

The Great Reset Incorporates All These Ideas Into Its Plans

Publicly, the WEF states The Great Reset is going to be about completely revamping capitalism.

“Every industry, from oil and gas to tech, must be transformed. In short, we need a ‘Great Reset’ of capitalism.” – The WEF 

The WEF particularly likes to say they want to instigate “stakeholder capitalism,” where the bulk of the private sector works hand in hand with the government. They say that such “will require stronger and more effective governments.” According to the WEF, there are human and financial costs of capitalism not being addressed. 

What do you call it when the government owns and controls all private business?

Communism. You call it communism.

And, what happens when capitalism dies?

As Ayn Rand pointed out in her excellent book Capitalism: The Unknown Ideal, man on this earth without capitalism is bound. It’s inseparable from true human freedom. Collectivism leads to further and further slavery every single time.

The Fourth Industrial Revolution

A significant component of The Great Reset is a term Schwabb coined back in December 2015 – The Fourth Industrial Revolution. The best way to describe it is to combine The Matrix, Minority Report, and Will Smith’s I, Robot.

According to Schwabb, the goal of The Fourth Industrial Revolution is “Ubiquitous, mobile supercomputing. Intelligent robots. Self-driving cars. Neuro-technological brain enhancements. Genetic editing. The evidence of dramatic change is all around us, and it’s happening at exponential speed.”

In Short, Schwabb Wants To Turn The World Into A Digital Mecca

Perhaps you don’t care about the above “improvements” – they don’t bother you? Well, let’s continue to delve deeper.

As it is, the WEF has already alluded to the possibility of using an AI to govern humanity. Humans would no longer have elected representatives in office (not that the US has that now, but I digress). Instead, super-powerful AI would determine what supplies went where and what prices would be, and so on. 

It’s the surrender of humanity to a machine.

Furthermore, What About These Brain Enhancements And Genetic Editing?

Look around at the world before you and what “the powers that be” have forced upon society. In a world full of brain enhancements and genetic editing, do you genuinely think you would still be free to choose?

Remember that The Fourth Industrial Revolution heavily ties in with The Great Reset, which seeks a one-world government. In such a world, should it be decreed under the guise of law that overpopulation is a problem, the ability to genetically edit sterility into 20% of the population becomes a reality. Let’s say the lottery system selects both of your kids. Do you really think they would grant you a say?

Freedom Would Have Long Been Rotting In The Grave In Such A World.

Further aspects of The Fourth Industrial Revolution include digital surveillance everywhere, made possible worldwide by 5G (with the hope of utilizing 6G eventually).  

There would be no privacy in such a world. It would be Nazi Germany on steroids. Have you read Zamyatin’s dystopian novel We (in many ways, the inspiration for 1984)? Practically, you’d be living in a world of glasshouses.

It’s worth noting that there are several other aspects of TGR that bear mentioning. Consider the following:

Rural Populations Will Be Forcibly Coerced Into Urban Environments 

Allegedly, to combat climate change. In reality, it is to have easier control over potential dissidents. It doesn’t matter if you don’t want to leave your farm. The good of the whole compels you, and men who have heartily devoured Mao Zedong’s philosophy on power (“Political power only grows out of the barrel of a gun.”) will be happy to assist you in your mental transition here. 

Citizens Now Rent Everything Because They Own Nothing

Aden Tate wrote about what the world would like like without personal property in this article. Aden writes, “Within the World Economic Forum’s Great Reset, the mantra has come out that by the year 2030, ‘you’ll own nothing. And you’ll be happy.’”

The government now owns everything, as a group of men comes in to tell you they are stealing what is rightfully yours. The world falls back to a system of feudalism. The Irish are well-familiarized with how such a system works out. 

All Media Is Digital

Climate change, of course. And let’s not forget the recent trend to battle “disinformation’. If everything is digital, it is censorable. This serves as the ultimate means of wholly controlling what it is people read and say. 

A Chinese-Style Social Credit System

Good global citizens of the one-world government will have a higher social credit score than the older American who supports those fighting against foreign invaders. These higher scores will permit access to travel “privileges,” better food, and better jobs. And in a world full of brain implants and genetic editing, I wonder what some of the punishments for low-scoring Americans could be? 

A Digital Blockchain Currency Is Now The Way Forward

Cash becomes a vector of disease, expensive to produce, and inefficient. Of course, this means they can track every purchase you ever make.  There is no anonymity of purchases any longer. Given the new ability to pay for food with your palm, the push for using a QR code to pay for anything, and quantum dot tattoos that may be able to store your financial data, this may not be too far off.

What’s For Dinner? Bugs And Fake, Food-Like Lab Products

According to The Great Reset, animals are a “resource-intensive” form of protein. The GR seeks to steer you away from such foods and “towards four main categories of alternatives – aquatic, plant-based, insect-based, and laboratory-cultured.”  

The Great Reset And The World Economic Forum Are NOT Your Friends

Should The Great Reset succeed, the world will firmly fall into the grip of a totalitarian government. You will be a slave in every sense of the word, liable to medical experimentation and forced treatments. The state will own your children, and if history serves as a guide, you won’t get to keep them for long. Should the AI determine it’s convenient, your family will be uprooted and transferred to a newly created ghetto.

Forced to ingest chemicals rather than food, you will never know what genetic-altering agents and medications are in those foods. 

Your lifelong dream to be a parent could be vaporized as mandates of forced sterility begin. Should woke culture decide masculine men are an issue, would it be outside the scope of the power of a government that owns everything to mandate the creation of eunuchs throughout your town?

Though the rest of the world may have fallen, Americans can never let their country follow suit.

Too much depends upon it.

By Jeff Thompson, TheOrganicPrepper.com

We Are at War

We are at war. Yes. And I don’t mean the West against the East, against Russia and China, nor the entire world against an invisible corona virus.

No. We, the common people, are at war against an ever more authoritarian and tyrannical elitist Globalist system, reigned by a small group of multi-billionaires, that planned already decades ago to take power over the people, to control them, reduce them to what a minute elite believes is an “adequate number” to inhabit Mother Earth – and to digitize and robotize the rest of the survivors, as a sort of serfs. It’s a combination of George Orwell’s “1984” and Aldous Huxley’s “Brave New World”.

Welcome to the age of the transhumanism. If we allow it.

Vaccination

That’s why vaccination is needed in warp speed, to inject us with transgenic substances that may change our DNA, lest we may wake up, or at least a critical mass may become conscious – and change the dynamics. Because dynamics are not predictable, especially not in the long-term.

The war is real and the sooner we all realize it, the sooner those in masks and those in social distancing take cognizance of the worldwide “anti-human” dystopian situations we have allowed our governments to bestow on us, the better our chance to retake our sovereign selves.

Today we are confronted with totally illegal and oppressive rules, all imposed under the pretext of “health protection”.

Non-obedience is punishable by huge fines; military and police enforced rules: Mask wearing, social distancing, keeping within the allowed radius of our “homes”, quarantining, staying away from our friends and families.

Actually, the sooner, We, the People, will take up an old forgotten characteristic of human kind – “solidarity” – and fight this war with our solidarity, with our love for each other, for mankind, with our love for LIFE and our Love for Mother Earth, the sooner we become again independent, self-assured beings, an attribute we have lost gradually over the last decades, at the latest since the beginning of the neoliberal onslaught of the 1980s.

Slice by tiny slice of human rights and civil rights have been cut off under false pretexts and propaganda – “security” – to the point where we, drowned in propagated dangers of all kinds, begged for more security and gladly gave away more of our freedoms and rights. How sad.

Now, the salami has been sliced away.

We suddenly realize, there is nothing left. Its irrecoverable.

We have allowed it to happen before our eyes, for promised comfort and propaganda lies by these small groups of elitists – by the Globalists, in their thirst for endless power and endless greed – and endless enlargements of their riches, of their billions. – Are billions of any monetary union “riches”? – Doubtfully. They have no love. No soul, no heart just a mechanical blood-pump that keeps them alive, if you can call that a “life”.

These people, the Globalists, they have sunk so deep in their moral dysfunction, totally devoid of ethics, that their time has come – either to be judged against international human rights standards, war crimes and crimes against humanity – similar as was done by the Nuremberg Trials after World War II, or to disappear, blinded away by a new epoch of Light.

As the number of awakening people is increasing, the western Powers that Be (PTB) are becoming increasingly nervous and spare no efforts coercing all kinds of people, para-government, administrative staff, medical personnel, even independent medical doctors into defending and promoting the official narrative.

It is so obvious, when you have known these people in “normal” times, their progressive opinions suddenly turning, by 180 degrees, to the official narrative, defending the government lies, the lies of the bought “scientific Task Forces” that “advise” the governments, and thereby provide governments with alibis to “tighten the screws” a bit more (Ms. Merkel’s remarks) around the people, the very people the governments should defend and work for; the lies and deceptive messages coming from “scientists” who may have been promised “eternal, endless ladders of careers”, or of lives in a hidden paradise?

What more may they get in turn for trying to subvert their friends’, peers’, patients’ opinions about the horror disease “covid-19”? – Possibly something that is as good as life itself – and is basically cost free for the avaricious rich. For example, a vax-certificate without having been vaxxed by the toxic injections, maybe by a placebo – opening the world of travel and pleasurable activities to them as “before”.

By the way, has anybody noticed that in this 2020 / 2021 winter flu-season, the flu has all but disappeared? – Why? – It has conveniently been folded into covid, to fatten and exaggerate the covid statistics. It’s a must, dictated by the Globalists, the “invisible” top echelon, whose names may not be pronounced. Governments have to comply with “covid quotas”, in order to survive the hammer of the Globalists.

Other special benefits for those selected and complacent defender of the official narrative, the placebo-vaxxed, may include dispensation from social distancing, mask wearing, quarantining – and who knows, a hefty monetary award. Nothing would be surprising, when you see how this tiny evil cell is growing like a cancer to take over full power of the world – including and especially Russia and China, where the bulk of the world’s natural resources are buried, and where technological and economic advances far outrank the greed-economy of the west. They will not succeed.

What if the peons don’t behave? – Job loss, withdrawal of medical licenses, physical threats to families and loved ones, and more.

Screen Shot: NTD, December 16, 2020

The Globalists evil actions and influence-peddling is hitting a wall in the East, where they are confronted with educated and awakened people.

We are at war. Indeed. The 99.999% against the 0.001%.

Their tactics are dividing to conquer, accompanied by this latest brilliant idea – launching an invisible enemy, a virus, a plandemic, and a fear campaign to oppress and tyrannize the entire world, all 193 UN member countries.

The infamous words, spoken already more than half a century ago by Rockefeller protégé, Henry Kissinger, comes to mind:

“Who controls food supply controls the people; who controls the energy can control whole continents; who controls money can control the world.”

Quoted below are some lines and thoughts of a 1 January 2021, RT Op-Ed article by Helen Buyniski entitled “Civil war, medical discrimination, spy satellites and cyborgs! How 2021 could make us yearn for 2020”. The article may point us in a direction of what may happen in 2021, that we certainly do not yearn for:

“People everywhere are eager to bid farewell to 2020, a year in which our lives were turned upside down by power-mad elites who seized the Covid-19 pandemic as a chance to go full police state.

But be careful what you wish for…. merely putting up a new calendar does nothing to address [the mounting repression and tyranny], which seem certain to reach a breaking point.

Humanity has been pushed to the limit with arbitrary rules, enforced poverty, and mandated isolation — it will only take a spark or two for things to explode.”

And it continues –

”As vaccines are rolled out to the general public, the divide between those obeying the rules and the dissidents will only grow. Those who decline to get the jab will be treated as pariahs, banned from some public spaces and told it’s their fault life hasn’t gone back to normal, just as so-called “anti-maskers” have been.”

And more glorious prospects

“Anyone who isn’t thrilled by the idea of ingesting an experimental compound whose makers have been indemnified from any lawsuits, will be deemed an enemy of the state, even separated from their children or removed from their home as a health risk. Neighbors will gleefully rat each other out for the equivalent of an extra chocolate ration, meaning even the most slavishly obedient individuals could end up in “quarncentration camps” for upsetting the wrong person.”

Yes, we are in the midst of war.

A war that has already ravaged our society, divided it all the way down to families and friends.

If we are not careful, we may not look our children and grandchildren in the eyes, because we knew, we ought to have known what was and is going on, what is being done, by a small dark power elite – the Globalists. We must step out of our comfort zone, and confront the enemy with an awakened mind of consciousness and a heart filled with love – but also with fierce resistance.

If we fail to step up and stand up for our rights, this war goes on to prepare future generations – to abstain from congregating with other people.

They are already indoctrinating our kids into keeping away from friends, school colleagues, peers, and from playing in groups with each other – as the New Normal.

The self-declared cupula – the crème of the crop of civilization – the Globalist evil masters, already compromised and continue to do so, the education systems throughout the globe to instill into kids and young adults that wearing masks is essential for survival, and “social distancing” is the only way forward.

Must see Video

Children of the Great Reset

How The Internet Of Bodies (IoB) Will Literally Connect You To The Internet

Privacy and security experts have been warning about Internet of Things (IoT) technology for many years and continue to do so (see 1, 2, 3, 4). Internet of Bodies (IoB) technology falls under the IoT umbrella and it is currently unregulated.

For those who aren’t familiar with what IoT entails, an excellent description has been provided on the Whatis5G.Info website:

The Internet of Things (IoT), as being marketed and sold to the public, is a vision of connecting every “thing” possible to the Internet – all machines, appliances, objects, devices, animals, insects and even our brains.

In addition, the IoT will include artificial intelligence (AI), augmented reality (AR), virtual reality (VR), robots, microchipped humans, and augmented humans (humans with some form of technology implanted or integrated into their biology to “enhance” human characteristics or capabilities).

IoT sensors and surveillance cameras will pepper our communities as well. New IoT cyber physical systems will render all objects “smart” – i.e. connected to the Cloud – thus enabling pervasive machine-to-machine (M2M) communications and massive data collection and leaving us open to devastating cyber attacks.

In November, Activist Post reported about a law review article which revealed legal and social issues associated with both IoB and IoT technology.

Additional scary details and pictures were provided in an article published by Truth UnMuted:

The Internet Of Bodies (IoB) And Hacking Your DNA

How Implantable Devices Will Connect Your Body to the Internet

The age of the Internet of Things (IoT), and soon to follow the Internet of Bodies (IoB), is now upon us.

The RAND Corporation, the think tank behind some of the world’s most influential and frightening ideas and technologies, has released a report titled The Internet of Bodies: Opportunities, Risks, and Governance.

You should be wary of any reports issued by the RAND Corporation. Alex Abella, author of Soldiers of Reason: The RAND Corporation and the Rise of American Empire, explains why:

RAND was, and is, the essential establishment organization. Throughout its history, RAND has been at the heart of that interweaving of Pentagon concupiscence and financial rapacity that President Eisenhower aimed to call the military- industrial- legislative complex. RAND has literally reshaped the modern world—and very few know it.

With this understanding, there is much cause for alarm with the issuance of this new report.

What Is The Internet Of Bodies (IoB)?

RAND defines the IoB as “a growing industry of devices that monitor the human body, collect health and other personal information, and transmit that data over the Internet.”

In order to qualify as an IoB device, the technology must:

• contain software or computing capabilities
• be able to communicate with an Internet-connected device or network

An IoB device must also satisfy one or both of the following:

• collect person-generated health or biometric data
• be able to alter the human body’s function

The technology that Hollywood has presented over the years in dystopian sci-fi fantasies is now a reality.

In the very near future, the technocratic overlords of science, health, finance, and Big Tech desire humanity to go from wearable devices to devices embedded within our bodies.

How IoB Intersects With IoT

IoT devices such as smart meters, smart watches, virtual assistants, and self-driving cars connect directly to the Internet or through a local network.

As IoT devices become more commonplace, experts predict that acceptance of and desire for IoB devices will also increase. The RAND report predicts:

By 2025, there will be more than 41 billion active IoT devices, generating 2.5 quintillion bytes of data daily on environment, transportation, geolocation, diet, exercise, biometrics, social interactions, and everyday human lives. This explosion in IoT devices will result in further popularity of IoB devices.

IoB Products In Use Or Being Developed

Figure 1 from the RAND report shows just how invasive and pervasive IoB technology can become. By the time it is fully unleashed, no part of the human body will escape its interference. They even plan to have our toilets connected to the Internet where they will monitor our waste using BioBot technology to determine what we eat, what drugs we may take, and analyze our genetic material!

Here are just a few examples of the technology currently being developed:

• Augmented reality contact lenses
• Brain reading and writing devices
• Body-implanted sensors
• Clothing with sensors
• Implantable microchips (RFID and NFC)
• Mental and emotional sensors
• Artificial pancreas
• Bluetooth connected diaper

Not even babies will be able to escape this nightmare where every bodily function is constantly tracked and monitored. The sad part is that many people will welcome these intrusive technologies because they’re convenient and timesaving. However, exchanging bodily sovereignty for convenience is never a fair transaction. It almost always serves to benefit those who desire more control over our lives.

Through adoption of technological advancement, humans are consenting to allow technocrats to dictate every facet of life. Soon doctors will be able to know if you are taking prescribed medication appropriately, and will have tools to report you if you aren’t. Digital pills will be used to record your medical compliance as the RAND report signals – Read full article

As noted in the article, IoB technology requires wireless (WiFi) radiation, 5G and other Electromagnetic Fields (aka “Electrosmog”) in order to perform.  All of these sources are biologically harmful. So there’s that too.

‘Rogue’ Chinese Virologist Publishes ‘Smoking Gun’ Evidence COVID-19 Created In Lab

On Saturday we reported that Dr. Li-Meng Yan – a Chinese virologist (MD, PhD) who fled the country, leaving her job at a prestigious Hong Kong university – appeared last week on British television where she claimed SARS-CoV-2, the virus which causes COVID-19, was created by Chinese scientists in a lab.

On Sunday, Li-Meng joined Twitter – and on Monday, just hours ago, she tweeted a link to a paper she co-authored with three other Chinese scientists titled:

Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route

She also posted a link to her credentials on Research Gate, revealing her (prior?) affiliation with The University of Hong Kong and 13 publications which have been cited 557 times.

Cutting to the chase:

“The evidence shows that SARS-CoV-2 should be a laboratory product created by using bat coronaviruses ZC45 and/or ZXC21 as a template and/or backbone. Building upon the evidence, we further postulate a synthetic route for SARS-CoV-2, demonstrating that the laboratory-creation of this coronavirus is convenient and can be accomplished in approximately six months.”

Here is the extended punchline:

The receptor-binding motif of SARS-CoV-2 Spike cannot be born from nature and should have been created through genetic engineering.

The Spike proteins decorate the exterior of the coronavirus particles. They play an important role in infection as they mediate the interaction with host cell receptors and thereby help determine the host range and tissue tropism of the virus.

The Spike protein is split into two halves (Figure 3). The front or N-terminal half is named S1, which is fully responsible for binding the host receptor.

In both SARS-CoV and SARS-CoV-2 infections, the host cell receptor is hACE2. Within S1, a segment of around 70 amino acids makes direct contacts with hACE2 and is correspondingly named the receptor-binding motif (RBM) (Figure 3C).

In SARS-CoV and SARS-CoV-2, the RBM fully determines the interaction with hACE2. The C-terminal half of the Spike protein is named S2.

The main function of S2 includes maintaining trimer formation and, upon successive protease cleavages at the S1/S2 junction and a downstream S2’ position, mediating membrane fusion to enable cellular entry of the virus.

Similar to what is observed for other viral proteins, S2 of SARS-CoV-2 shares a high sequence identity (95%) with S2 of ZC45/ZXC21.

In stark contrast, between SARS-CoV-2 and ZC45/ZXC21, the S1 protein, which dictates which host (human or bat) the virus can infect, is much less conserved with the amino acid sequence identity being only 69%.

Figure 4 shows the sequence alignment of the Spike proteins from six β coronaviruses. Two are viruses isolated from the current pandemic (Wuhan-Hu-1, 2019-nCoV_USA-AZ1); two are the suspected template viruses (Bat_CoV_ZC45, Bat_CoV_ZXC21); two are SARS coronaviruses (SARS_GZ02, SARS).

The RBM is highlighted in between two orange lines.

Clearly, despite the high sequence identity for the overall genomes, the RBM of SARS-CoV-2 differs significantly from those of ZC45 and ZXC21.

Intriguingly, the RBM of SARS-CoV-2 resembles, on a great deal, the RBM of SARS Spike.

Although this is not an exact “copy and paste”, careful examination of the Spike-hACE2 structures37,38 reveals that all residues essential for either hACE2 binding or protein folding (orange sticks in Figure 3C and what is highlighted by red short lines in Figure 4) are “kept”.

Most of these essential residues are precisely preserved, including those involved in disulfide bond formation (C467, C474) and electrostatic interactions (R444, E452, R453, D454), which are pivotal for the structural integrity of the RBM (Figure 3C and 4).

The few changes within the group of essential residues are almost exclusively hydrophobic “substitutions” (I428àL, L443àF, F460àY, L472àF, Y484àQ), which should not affect either protein folding or the hACE2-interaction.

At the same time, majority of the amino acid residues that are non-essential have “mutated” (Figure 4, RBM residues not labeled with short red lines).

Judging from this sequence analysis alone, we were convinced early on that not only would the SARS-CoV-2 Spike protein bind hACE2 but also the binding would resemble, precisely, that between the original SARS Spike protein and hACE223. Recent structural work has confirmed our prediction.

As elaborated below, the way that SARS-CoV-2 RBM resembles SARS-CoV RBM and the overall sequence conservation pattern between SARS-CoV-2 and ZC45/ZXC21 are highly unusual.

Collectively, this suggests that portions of the SARS-CoV-2 genome have not been derived from natural quasi-species viral particle evolution.

The paper then makes two critical observations for those who claim that SARS-CoV-2 has a natural origin: its RBM could have only been acquired in one of the two possible routes:

1) an ancient recombination event followed by convergent evolution or

2) a natural recombination event that occurred fairly recently.

She first dismisses option 1:

“this convergent evolution process would also result in the accumulation of a large amount of mutations in other parts of the genome, rendering the overall sequence identity relatively low.

“The high sequence identity between SARS-CoV-2 and ZC45/ZXC21 on various proteins (94-100% identity) do not support this scenario and, therefore, clearly indicates that SARS-CoV- 2 carrying such an RBM cannot come from a ZC45/ZXC21-like bat coronavirus through this convergent evolutionary route.”

She then dismisses option 2:

In the second scenario, the ZC45/ZXC21-like coronavirus would have to have recently recombined and swapped its RBM with another coronavirus that had successfully adapted to bind an animal ACE2 highly homologous to hACE2.

The likelihood of such an event depends, in part, on the general requirements of natural recombination:

1) that the two different viruses share significant sequence similarity;

2) that they must co-infect and be present in the same cell of the same animal;

3) that the recombinant virus would not be cleared by the host or make the host extinct;

4) that the recombinant virus eventually would have to become stable and transmissible within the host species.

In regard to this recent recombination scenario, the animal reservoir could not be bats because the ACE2 proteins in bats are not homologous enough to hACE2 and therefore the adaption would not be able to yield an RBM sequence as seen in SARS-CoV-2.

This animal reservoir also could not be humans as the ZC45/ZXC21-like coronavirus would not be able to infect humans.

In addition, there has been no evidence of any SARS-CoV-2 or SARS-CoV-2-like virus circulating in the human population prior to late 2019.

Intriguingly, according to a recent bioinformatics study, SARS-CoV-2 was well-adapted for humans since the start of the outbreak.

Which leaves just one option:

Only one other possibility of natural evolution remains, which is that the ZC45/ZXC21-like virus and a coronavirus containing a SARS-like RBM could have recombined in an intermediate host where the ACE2 protein is homologous to hACE2.

Several laboratories have reported that some of the Sunda pangolins smuggled into China from Malaysia carried coronaviruses, the receptor-binding domain (RBD) of which is almost identical to that of SARS-CoV-227-29,31.

They then went on to suggest that pangolins are the likely intermediate host for SARS-CoV-227-29,31.

However, recent independent reports have found significant flaws in this data40-42. Furthermore, contrary to these reports27-29,31, no coronaviruses have been detected in Sunda pangolin samples collected for over a decade in Malaysia and Sabah between 2009 and 201943.

A recent study also showed that the RBD, which is shared between SARS-CoV-2 and the reported pangolin coronaviruses, binds to hACE2 ten times stronger than to the pangolin ACE22, further dismissing pangolins as the possible intermediate host.

Finally, an in silico study, while echoing the notion that pangolins are not likely an intermediate host, also indicated that none of the animal ACE2 proteins examined in their study exhibited more favorable binding potential to the SARS-CoV-2 Spike protein than hACE2 did.

This last study virtually exempted all animals from their suspected roles as an intermediate host, which is consistent with the observation that SARS-CoV-2 was well-adapted for humans from the start of the outbreak.

This is significant because these findings collectively suggest that no intermediate host seems to exist for SARS-CoV-2, which at the very least diminishes the possibility of a recombinant event occurring in an intermediate host.

Fast-forwarding to the smoking gun:

Given that RBM fully dictates hACE2-binding and that the SARS RBM-hACE2 binding was fully characterized by high-resolution structures (Figure 3)37,38, this RBM-only swap would not be any riskier than the full Spike swap.

In fact, the feasibility of this RBM-swap strategy has been proven. In 2008, Dr. Zhengli Shi’s group swapped a SARS RBM into the Spike proteins of several SARS-like bat coronaviruses after introducing a restriction site into a codon-optimized spike gene (Figure 5C). They then validated the binding of the resulted chimeric Spike proteins with hACE2.

Furthermore, in a recent publication, the RBM of SARS-CoV-2 was swapped into the receptor-binding domain (RBD) of SARSCoV, resulting in a chimeric RBD fully functional in binding hACE2 (Figure 5C)39.

Strikingly, in both cases, the manipulated RBM segments resemble almost exactly the RBM defined by the positions of the EcoRI and BstEII sites (Figure 5C).

Although cloning details are lacking in both publications39,47, it is conceivable that the actual restriction sites may vary depending on the spike gene receiving the RBM insertion as well as the convenience in introducing unique restriction site(s) in regions of interest.

It is noteworthy that the corresponding author of this recent publication, Dr. Fang Li, has been an active collaborator of Dr. Zhengli Shi since 201049-53.

Dr. Li was the first person in the world to have structurally elucidated the binding between SARS-CoV RBD and hACE238 and has been the leading expert in the structural understanding of Spike-ACE2 interactions.

The striking finding of EcoRI and BstEII restriction sites at either end of the SARS-CoV-2 RBM, respectively, and the fact that the same RBM region has been swapped both by Dr. Shi and by her long-term collaborator, respectively, using restriction enzyme digestion methods are unlikely a coincidence.

Rather, it is the smoking gun proving that the RBM/Spike of SARS-CoV-2 is a product of genetic manipulation.”

It gets better, because the Chinese scientists then presciently tried to cover their tracks:

Although it may be convenient to copy the exact sequence of SARS RBM, it would be too clear a sign of artificial design and manipulation. The more deceiving approach would be to change a few nonessential residues, while preserving the ones critical for binding.

This design could be well-guided by the high-resolution structures (Figure 3)37,38. This way, when the overall sequence of the RBM would appear to be more distinct from that of the SARS RBM, the hACE2-binding ability would be well-preserved.

We believe that all of the crucial residues (residues labeled with red sticks in Figure 4, which are the same residues shown in sticks in Figure 3C) should have been “kept”.

As described earlier, while some should be direct preservation, some should have been switched to residues with similar properties, which would not disrupt hACE2-binding and may even strengthen the association further [ZH: i.e., the virus was weaponized and enchanced].

Importantly, changes might have been made intentionally at non-essential sites, making it less like a “copy and paste” of the SARS RBM.

Yan also discusses the infamous furin-cleavage site:

… a close examination of the nucleotide sequence of the furin-cleavage site in SARS-CoV-2 spike has revealed that the two consecutive Arg residues within the inserted sequence (- PRRA-) are both coded by the rare codon CGG (least used codon for Arg in SARS-CoV-2) (Figure 7).

In fact, this CGGCGG arrangement is the only instance found in the SARS-CoV-2 genome where this rare codon is used in tandem. This observation strongly suggests that this furin-cleavage site should be a result of genetic engineering.

Adding to the suspicion, a FauI restriction site is formulated by the codon choices here, suggesting the possibility that the restriction fragment length polymorphism, a technique that a WIV lab is proficient at, could have been involved.

There, the fragmentation pattern resulted from FauI digestion could be used to monitor the preservation of the furin-cleavage site in Spike as this furin-cleavage site is prone to deletions in vitro.

Specifically, RT-PCR on the spike gene of the recovered viruses from cell cultures or laboratory animals could be carried out, the product of which would be subjected to FauI digestion.

Viruses retaining or losing the furin-cleavage site would then yield distinct patterns, allowing convenient tracking of the virus(es) of interest.

And another critical allegation: once again, the Wuhan Researchers were doing everything in their power to weaponize and boost the “enhancement of the infectivity and pathogenicity of the laboratory-made coronavirus“:

The evidence collectively suggests that the furin-cleavage site in the SARS-CoV-2 Spike protein may not have come from nature and could be the result of genetic manipulation.

The purpose of this manipulation could have been to assess any potential enhancement of the infectivity and pathogenicity of the laboratory-made coronavirus.

Summarizing the above:

Evidence presented in this part reveals that certain aspects of the SARS-CoV-2 genome are extremely difficult to reconcile to being a result of natural evolution.

The alternative theory we suggest is that the virus may have been created by using ZC45/ZXC21 bat coronavirus(es) as the backbone and/or template.

The Spike protein, especially the RBM within it, should have been artificially manipulated, upon which the virus has acquired the ability to bind hACE2 and infect humans.

This is supported by the finding of a unique restriction enzyme digestion site at either end of the RBM.

An unusual furin-cleavage site may have been introduced and inserted at the S1/S2 junction of the Spike protein, which contributes to the increased virulence and pathogenicity of the virus.

These transformations have then staged the SARS CoV-2 virus to eventually become a highly-transmissible, onset-hidden, lethal, sequelae-unclear, and massively disruptive pathogen.

Evidently, the possibility that SARS-CoV-2 could have been created through gain-of-function manipulations at the WIV is significant and should be investigated thoroughly and independently.

Finally, those curious how the virus could have been created synthetically in Wuhan, here is a diagram proposed by Dr. Yan explaining all the required steps: